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• Beyond sanity and madness

  Editorial p3

  Calling people "mad" not only dehumanises them, but makes it more difficult to benefit from their insights, too

• Aspirin, the cancer wonder drug

  Opinion p3

  The argument for even more widespread use of aspirin as a cancer prophylactic is starting to look unstoppable

• ADHD drugs do not cause sudden death

  News > Upfront p4

  Children treated for attention deficit hyperactivity disorder are no more likely to suffer stroke or heart failure than their unmedicated peers

• Row over plans to mine Grand Canyon

  News > Upfront p4

  While the government pushes to oppose new uranium mines in north Arizona, Republicans are working to overturn any ban

• World unites to discuss internet freedoms and dangers

  News > Upfront p4

  The first international conference on cyberspace brought together senior political figures and tech royalty from across the world

• China launches spacecraft to test automated docking

  News > Upfront pp4-5

  The Shenzhou-8 craft will attempt to dock with a prototype science lab launched in September – the procedure is an essential part of building a space station by 2020

• 60 Seconds

  News > 60 Seconds p5

  Transplant cancer trade-off, Soyuz back in business, moon camera returned, and more

• 'Astronauts' to emerge from 520-day mock Mars mission

  News > Upfront p5

  After being cooped up for a year-and-a-half in a simulated spaceship in Moscow, six men are due to return to Earth – data from the mission could help future astronauts

• US drug shortages blamed on foreign suppliers

  News > Upfront p5

  Foreign companies supplying cheap, lower quality drugs together with illegal "price gouging" are blamed for lack of prescription drugs in US

• US to test anthrax vaccine in children… maybe

  News > Upfront p5

  An ethical review will decide whether or not the US tests its anthrax vaccine in the nation's children

• Everyday drugs could stop cancers before they hit

  News > This Week pp6-7

  A daily dose of cheap drugs including aspirin and tamoxifen prevents common cancers from starting to develop, studies suggest

• Visit to the coral gardeners' seabed lab

  News > This Week p8

  The Aquarius Reef Base is a research lab like no other, offering an unmatched opportunity to research coral ecosystems, and test coral farming

• Most common stars are more life-friendly than thought

  News > This Week p9

  Small and cool they may be, but red dwarfs, the most common kind of star, are more likely to support life than we thought

• Seaways across Antarctica could open in 1000 years

  News > This Week p9

  As Antarctica melts, seaways will open up between oceans that are currently separated by the ice sheet

• Green tea and red laser attack Alzheimer's plaques

  News > This Week p12

  Lasers can force drugs into cells to destroy the plaques that cause memory loss in Alzheimer's disease

• Nuclear clock could steal atomic clock's crown

  News > This Week p12

  The ultimate timekeeper – the atomic clock – has a rival, thanks to a new method for making clocks based on manipulating the atomic nucleus

• Trade war looms over Europe's aircraft carbon tax

  News > This Week p14

  The world could be on the brink of a trade war over European Union efforts to impose carbon charges on the emissions of all planes landing or taking off within the EU

• Sabre-toothed squirrel scurried at dinosaurs' feet

  News > This Week p15

  The fossil of a mammal that lived in the shadow of the dinosaurs and was a dead ringer for the sabre-toothed squirrel star of Ice Age fame has been found

• Tough astronaut bugs to blast off for Mars moon

  News > This Week p15

  Russia's Phobos-Grunt spacecraft will carry some of Earth's toughest organisms as passengers to test the idea that life could planet-hop in meteoroids

• Dreams read by brain scanner for the first time

  News > This Week p16

  With the help of six rare lucid dreamers, scanners have shown that brain activity when dreaming an action is similar to that of imagining it

• Cat's eye irises don't need brain to adapt to the dark

  News > In Brief p18

  The muscles controlling the slit-like pupil of a cat's eye do not need nerve signals to move – a light-sensitive pigment in the iris can do the job instead

• Slime killer hagfish feasts in rotten flesh

  News > In Brief p18

  Despite not having any jaws, hagfish hunt fish, deter predators with slime, and eat rotting corpses from the inside out

• Stem-cell find breathes new life into lung repair

  News > In Brief p18

  New hopes of treating chronic lung diseases have been raised by the rapid stem-cell repair of mouse lungs

• Undead stars rise again as supernovae

  News > In Brief p18

  If a tribe of dormant, winking stars really are on the verge of going supernova, they will help reveal dark energy's true nature

• A shot of snake blood makes the heart grow

  News > In Brief p19

  Fatty acids found in snake blood increase heart size and efficiency, and could one day be used to treat damaged hearts

• Blood platelets get a new job: fighting invaders

  News > In Brief p19

  It was assumed that platelets primarily help blood to clot – now it appears they are also key to forming a full-blown immune response

• Most pristine known asteroid is denser than granite

  News > In Brief p19

  The lumpy asteroid Lutetia may be a whole, unbroken building block left nearly untouched since the solar system's birth

• Spider play sex isn't all fun and games

  News > In Brief p19

  Play sex tires males out, so others can drive them off and claim the now experienced female for themselves

• Casino cheats snared by smart camera system

  Technology > News p21

  Software installed in casino CCTV system could alert croupiers when players try to pull a fast one

• Artificial intelligence joins the fossil hunt

  Technology > News pp22-23

  Smart software that scans satellite images of potential dig sites could improve palaeontologists' luck at unearthing old bones

• Cotton transistors weave comfort into electronics

  Technology > News pp22-23

  The next generation of wearable electronics could be a lot more comfy, thanks to transistors made from cotton fibres

• Military robots can leave operators at home

  Technology > News p24

  Ground robots could soon be carrying out dangerous missions abroad while their operators control them from the US

• Report questions long-term safety of composite planes

  Technology > News p24

  Boeing's 787 is a technological marvel – but do ground engineers know how to check and maintain these part-plastic planes?

• See gull take on eagle in mid-air piggyback attack

  Aperture pp26-27

  A remarkable image of a white-tailed eagle under attack proves that gulls are utterly fearless

• 'Nudge' policies are another name for coercion

  Comment and Analysis pp28-29

  From organ donation to buying a pension, indirect attempts to sway behaviour undermine the core of democracy, say Henry Farrell and Cosma Shalizi

• Shuttle's last spacewalker: 'Gravity is an option'

  Opinion > Interview p29

  Earlier this year, Greg Chamitoff went on the last-ever spacewalk by shuttle astronauts. He tells New Scientist what it felt like

• The origin of sex was interaction, not reproduction

  Opinion > The Big Idea pp30-31

  Sex is a pretty primitive business, but it has so many downsides that its success is still a big evolutionary puzzle. Time for a rethink, says Thierry Lodé

• Facts on the ground

  Letters p32

  In your story on the lawsuit against TransCanada's Keystone XL Pipeline in North America, the statement that our legal challenge is about "nothing more"...

• Information input

  Letters p32

  Max Tegmark has two suggestions for what will happen to the information in an expanding universe: either information is created, meaning we can no longer...

• Navigation nostrums

  Letters p32

  One reason for the slow uptake of electronic navigation on ships (22 October, p 26) is the lack of adoption of open standards by the...

• Original spin

  Letters p32

  Anil Ananthaswamy's feature on the possibility of a spinning cosmos (15 October, p 44) had me reaching for a copy of Austrian logician Kurt...

• Enigma Number 1671

  Opinion > Enigma p32

• Baby nose best

  Letters p33

  The importance of the smell of the nipple for breastfeeding (8 October, p 12) is beautifully illustrated by a tale told to us by a...

• Blade runner

  Letters p33

  You describe a wind turbine with extendable blades (22 October, p 26). Why would they be better than blades that vary their pitch - their angle...

• Consistent we are

  Letters p33

  Your story "I'm autistic, I don't care what you think" was interesting (15 October, p 19). I have autism, and I think researcher...

• Copernican caveat

  Letters p33

  Further to your review of Dava Sobel's book on the heliocentric theory of Copernicus (24 September, p 61), the Polish astronomer was not alone...

• For the record

  Letters p33

  • In the Spaceport America story (22 October, p 12) we mistakenly said that Richard Branson is Virgin Galactic's CEO - he's the founder...

• Forest not so fine

  Letters p33

  Your article on the study of habitat fragmentation in Borneo carried out in co-operation with loggers states that 75,000 hectares of primary forest...

• Ripe economics

  Letters p33

  Feedback is right to welcome the removal of the wasteful "sell-by" date from food packaging (15 October, p 64) but misses a more ironic...

• Sticks and pyramids

  Letters p33

  With reference to the controversy over Tutankhamun's club foot (8 October, p 10), Zahi Hawass, while Egypt's antiquities minister, gave an apparently convincing...

• Wise old bird

  Letters p33

  The speculation, in an article on the evolution of our brains, that a dinosaur or bird could have evolved considerable intelligence instead of us was...

• Mental problems gave early humans an edge

  Features > Feature pp34-37

  Did an autistic inventor start a Stone Age technological revolution? Were the first spiritual leaders bipolar? A daring new theory makes the case

• The beetle plague devastating North America's forests

  Features > Feature pp38-41

  Bark beetles have been using all-out biological and chemical warfare to massacre vast swathes of North America's pine trees. Can nothing stop them?

• The underhand ape: Why corruption is normal

  Features > Feature pp42-45

  If you think you're incorruptible, think again. Understanding why so many right-thinking people behave deviously could help clean up business and politics

• Switzerland's medtech prowess

  Careers > The Insider pp50-51

  A tradition of precision watch-making has helped make tiny Switzerland a force to be reckoned with in medical technology, says Andrew Purcell

• Superconductors: 100 years on

  Features > Instant Expert

  Applications may have been slow in coming, yet how can you fail to be impressed when you look at an MRI scanner?

• Superconductors: Cold beginnings

  Features > Instant Expert

  It took more than half a century to figure out how superconductivity might work and how to make it useful

• Superconductors: Getting warmer

  Features > Instant Expert

  What we really want is a superconductor that operates at room temperature. Might one be within our grasp?

• Superconductors: What they're good for

  Features > Instant Expert

  Already used in applications as diverse as body scanning and discovering the origin of mass, superconductors hold promise for even greater technologies

• So you want to design your baby?

  Opinion > CultureLab p46

  Bart Fauser and Paul Devroey provide an authoritative tour of the intricacies, pitfalls and ethical labyrinths of assisted conception in Baby-Making

• A tour through our self-delusions

  Opinion > CultureLab p47

  In You Are Not So Smart, David McRaney lays out in entertaining detail four dozen of the ways we trick ourselves every day

• Quantum mechanics difficult to grasp? Too bad

  Opinion > CultureLab p47

  Trying to fit quantum mechanics to a paradigm we can readily understand misses the point, argue physicists Jeff Forshaw and Brian Cox in The Quantum Universe

• The best science tattoos and the stories behind them

  Opinion > CultureLab p48

  Carl Zimmer presents a beautifully curated selection of science-related tattoos in Science Ink

• Feedback: Don't believe your eyes

  Feedback p60

  Arks, gardens and creation, many hands make particle physics work, how not to do calorie restriction, and more

• Blacksmith's dilemma

  The Last Word > Last Word Answer p61

• Four-star review

  The Last Word > Last Word Question p61