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• Antibiotics are wonder drugs no more

  Editorial p5

  The side effects of antibiotics may make the war on hostile bacteria trickier to wage than ever

• We can't see the Milky Way's woods for its trees

  Editorial p5

  You might be forgiven for assuming that our home galaxy holds few mysteries. But you would be wrong

• A fifth of US pharmacies refuse teens contraception

  News > Upfront p6

  Teens legally entitled to emergency contraception were refused by 19 per cent of pharmacies compared with 3 per cent of GPs calling on their behalf

• Fracking could foil carbon capture plans

  News > Upfront p6

  Hydraulic fracturing brings us lots of natural gas, but it could also ruin the rock formations needed to store carbon dioxide underground

• Pressure to tighten up antibiotics on US farms

  News > Upfront p6

  Farmers in the US may soon be banned from giving antibiotics to healthy animals to prevent spread of drug resistance

• Ship formerly known as Exxon Valdez to be scrapped

  News > Upfront p6

  The oil tanker, which ran aground off Alaska in 1989 and spilled vast quantities of oil, has been sold for scrap

• 60 Seconds

  News > 60 Seconds p7

• Bacteria could be significant cause of OCD

  News > Upfront p7

  With growing evidence of a link between an unusual form of OCD in children and Streptococcus bacteria, trials involving an antibacterial treatment have begun

• Neutrino funding crunch could be good news for protons

  News > Upfront p7

  Hard times for the US's largest neutrino experiment could have an unexpected upside, speeding up the search for the elusive decay of a proton

• Antibiotics may make you fat

  News > This Week pp8-9

  The widespread use of antibiotics may permanently change our gut flora, increasing our risk of obesity and damaging our immune systems

• Methane cuts could delay climate change by 15 years

  News > Special Report pp10-11

  An atmosphere with less methane would encourage plants to soak up more carbon dioxide, buying precious time to solve the climate problem

• Arctic sea ice may have passed crucial tipping point

  News > Special Report p11

  The ice has not recovered from a record low in 2007 – ice-free summers could soon become a regular feature across most of the Arctic Ocean

• Arctic sea ice may have passed crucial tipping point

  News > Special Report p11

  The ice has not recovered from a record low in 2007 – ice-free summers could soon become a regular feature across most of the Arctic Ocean

• Black Queen tells microbes to be lazy

  News > Field Notes p12

  Microorganisms are in a constant, never-ending struggle: to make someone else do the hard work

• Entering the world's premier antimatter factory

  News > Field Notes p12

  New Scientist visits CERN's antimatter lab to find out why we should care about this slippery stuff

• Lightning directed by laser beams

  News > This Week p14

  For the first time, lasers have triggered and diverted lightning bolts

• Clocking galaxy clusters to gauge dark energy

  News > This Week p15

  Combining the afterglow of the big bang with a map of galaxy clusters reveals how the clusters move, which could provide a new way to measure dark energy

• Classical music affects heart transplants

  News > In Brief p16

  Mice with heart swaps survived twice as long when they listened to classical rather than pop music after their operation

• Dolphin social networks are unusually open

  News > In Brief p16

  Male dolphins don't live in tribes, but they form complex alliances with each other

• False memories generated in lab mice

  News > In Brief p16

  Researchers have found new ways to track neurons that encode memories, and even manipulate them to create virtual memories

• Zoologger: First animal with ovaries on the outside

  News > In Brief p16

  A newly discovered marine worm has external ovaries, and may use them to keep its young close until they're grown

• Earth has little to fear from a black hole attack

  News > In Brief p17

  Small black holes that may be roaming space undetected would leave Earth unscathed if they hit us

• Fossil raindrops reveal Earth's early atmosphere

  News > In Brief p17

  Analysis of a fossilised rain shower suggests air density on early Earth was similar to now, confounding explanations for the "faint sun paradox"

• Sensitive blood test detects cancer's comeback

  News > In Brief p17

  A blood test that can spot the return of breast cancer up to two years earlier than existing tests could soon be available

• Square galaxy is a rebel

  News > In Brief p17

  A rare rectangular galaxy spotted 700 million light years from Earth could offer new insight into the way galaxies form and evolve

• Driverless cars ready to hit our roads

  Technology > News pp19-20

  Sceptical about autonomous cars? Too late. They're already here – and they're smarter than ever

• New search tool to unlock Wikipedia

  Technology > News pp20-21

  Powerful new software called Swipe could handle complex queries that today's keyword search engines stumble over

• Photon sieves make super-cheap space telescopes

  Technology > News pp20-21

  A plastic sheet called a "photon sieve" focuses incoming light, providing a quick, cheap way to replace damaged space telescopes

• Bruisable gadgets heal themselves in the sun

  Technology > News p22

  A new type of plastic turns red when it is damaged – and then heals itself when exposed to light

• Crowdfunding successes show value of small donations

  Technology > News p22

  A proposed change in US legislation would allow everyone to invest in start-ups

• See the cities that never sleep from space

  Aperture pp24-25

  This image of the eastern US taken from the International Space Station shows that when the sun goes down, the Big Apple is far from alone

• How Canada's green credentials fell apart

  Comment and Analysis pp26-27

  Canada once enjoyed a deserved reputation for scientific and environmental leadership. Those days are long gone, says Bob Holmes

• Would you pay to block your own internet connection?

  Opinion > Interview p27

  Researcher Fred Stutzman has come up with apps to keep your mind on work and off the temptations of the web and social media

• Galactic laser light show might lead us to aliens

  Interview pp28-29

  Geoff Marcy is a prolific planet hunter, but now he's turning his gaze to alien civilisations. He hopes they may be criss-crossing space with laser beams

• Collateral damage

  Letters p30

  Your editorial statement that the Fukushima Daiichi nuclear meltdown has "so far killed no one" is undoubtedly untrue (10 March, p 3). Some 200,000...

• Eruption odds

  Letters p30

  I greatly enjoyed your deep future special, but was surprised to read that the chance of a supervolcano erupting in the next 100,000 years...

• Fonnetik fyoocher

  Letters p30

  A complementary question to your future-gazing article "What will we speak?" (3 March, p 39) is "How will we write?" If current trends in...

• Museum on the moon

  Letters p30

  Looking into the next 100,000 years of humanity, Bob Holmes asks what our descendants will know about us (3 March, p 48). He points...

• Teach science

  Letters p30

  You rightly inveigh against the polluting of science teaching with falsehoods such as climate scepticism, intelligent design and creationism (25 February, p 3). But isn...

• Year zero

  Letters p30

  Your special on "The deep future" (3 March, p 34) is accompanied by a timeline featuring the year zero. When Christians superimposed their BC-AD...

• Enigma Number 1691

  Opinion > Enigma p30

• Underground nukes

  Letters pp30-31

  Fred Pearce brings home the sheer complexity of decommissioning nuclear reactors (10 March, p 46). With 138 shut down and many more to come, it...

• For the record

  Letters p31

  • We should have said there is no chance of electrocution by the "Splash Controller" because "just 5 volts drive current through the water" (10 March...

• I, rapper robot

  Letters p31

  I recently wrote to argue that a robot is capable of creativity (4 February, p 31). So it is possible that cognitive dissonance is deterring...

• Polar p-p-p-pick up

  Letters p31

  Neil Padley suggests relocating polar bears to Antarctica, and wonders how many penguins a bear could eat (18 February, p 33...

• Seeds of doom

  Letters p31

  You report that visitors to the Antarctic carry, on average, 10 plant seeds (10 March, p 5). Do all tourists do the same to wilderness...

• The beauty of books

  Letters p31

  I make my living from the digital industry, but nothing angers me more than the berating of paper as an outmoded medium. David Weinberger lent...

• Wolf diet

  Letters p31

  Sharon Levy wrote that before 2001, wolves in Algonquin Provincial Park in Ontario, Canada, "would seldom take down a moose", using this statement to support...

• Milky Way mysteries: Antimatter factory

  Features > Cover Story pp32-33

  Our galaxy produces 10 billion tonnes of antimatter every second. What could be pumping out so many positrons?

• Milky Way mysteries: Five oddities of our galaxy

  Features > Cover Story pp33-36

  From a supermassive black hole to blue stragglers, we round up a quintet of our galaxy's most puzzling objects

• Milky Way mysteries: Our galaxy's shape

  Features > Cover Story p34

  Our lowly viewpoint in the galactic disc means we struggle to trace the Milky Way's outline, but new mapping methods could finally reveal its true face

• Milky Way mysteries: Andromeda, our sibling rival

  Features > Cover Story p35

  We used to think the Andromeda and the Milky Way were near-twins but it seems one is a golden child and the other an oddball

• Milky Way mysteries: Disappearing dwarf galaxies

  Features > Cover Story p35

  We know of 26 small galaxies orbiting the Milky Way, but theories of dark matter suggest we should have an army of them. So where are the lost legions?

• Milky Way mysteries: Fast-moving clouds defy gravity

  Features > Cover Story p36

  We thought the Magellanic clouds were part of our entourage, but they may just be two charismatic space tourists

• Milky Way mysteries: Where are all the supernovae?

  Features > Cover Story p36

  The Milky Way should host about three stellar explosions per century, but in the past millennium and a bit we have seen only five or six

• Orca invasion: Killer whales in a warmer world

  Features > Feature pp37-39

  As the sea ice recedes in Hudson Bay, killer whales are moving in for a feast. Are they eating the Inuit people's lunch?

• Sleeper cells: How to fight bacteria that play dead

  Features > Feature pp40-43

  Our strongest antibiotics are being thwarted by microbes that can lie dormant, only to reawaken once the threat has passed

• Impossible explosion: The Buncefield blast explained

  Features > Feature pp44-47

  Could trees and bushes have been to blame for the force of one of Europe's biggest peacetime explosions? Violent experiments may now have solved this enigma

• How robotics can offer clues to evolution

  Opinion > CultureLab p48

  In Darwin's devices: What evolving robots can teach us about the history of life and the future of technology, John Long explores a new way to study evolution

• Lifting the lid on Schrödinger's world

  Opinion > CultureLab p48

  In Erwin Schrödinger and the Quantum Revolution, John Gribbin unpicks the influences that shaped the work of the great quantum physicist

• Four billion years of Earth's shifting seasons

  Opinion > CultureLab p49

  In The Goldilocks Planet, palaeoclimatologists Jan Zalasiewicz and Mark Williams lay out how the climate has varied throughout Earth's history. It's a tall order.

• The likelihood of waking up dead

  Opinion > CultureLab p49

  In The Undead, Dick Teresi explores how ill-defined death is by the medical profession, and just how often it can be misdiagnosed

• Feedback: Historic stardom of number 42

  Feedback p64

  A potted history of 42, the balloon burglar, when off means almost on, and more...

• Golden wonder

  The Last Word > Last Word Answer p65

• Two of a kind

  The Last Word > Last Word Answer p65

• Rotten luck?

  The Last Word > Last Word Question p65